I get the appeal, I really do. The idea of wiping out a devastating genetic disease before a child is born is genuinely powerful, and anyone who says otherwise isn't taking the suffering of those families seriously. But the science just isn't there to support jumping in. The problem is we don't fully understand what we're doing. CRISPR can make precise cuts, but the embryo's own repair mechanisms are messy. Off-target edits are real, and we can't reliably detect them without destroying the embryo. Mosaicism means some cells get edited and some don't, so you end up with a child who's a patchwork of corrected and uncorrected DNA. That's not a cure, that's a gamble with a human life that can't consent. And there's no peer-reviewed evidence that these risks are manageable. Until we have longitudinal data, safety data, we'd be using people as experiments. That's not medicine. That's hubris.

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